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The 28-day mark is not a chemical cliff, and a vial punctured twice with good technique is not meaningfully different on day 30 than on day 27

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Β-Lapachone protects against doxorubicin-induced nephrotoxicity via NAD(+)/AMPK/NF-kB… [PMID: 30671613] Laboratory literature summary: β-Lapachone protects against doxorubicin-induced nephrotoxicity via NAD(+)/AMPK/NF-kB in mice